PlasmaMutationDetector: Tumor Mutation Detection in Plasma

Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples.

Version: 1.7.2
Depends: R (≥ 3.4.0), ggplot2 (≥ 2.2.0), grid (≥ 3.4.0), GenomicRanges (≥ 1.30.0), VariantAnnotation (≥ 1.24.0)
Imports: S4Vectors (≥ 0.16.0), Rsamtools (≥ 1.30.0), rtracklayer (≥ 1.38.0), robustbase (≥ 0.92-8), SummarizedExperiment (≥ 1.8.0)
Published: 2018-06-11
Author: Yves Rozenholc, Nicolas Pécuchet, Pierre Laurent-Puig
Maintainer: Yves Rozenholc <yves.rozenholc at parisdescartes.fr>
License: MIT + file LICENSE
NeedsCompilation: no
CRAN checks: PlasmaMutationDetector results

Documentation:

Reference manual: PlasmaMutationDetector.pdf

Downloads:

Package source: PlasmaMutationDetector_1.7.2.tar.gz
Windows binaries: r-devel: PlasmaMutationDetector_1.7.2.zip, r-release: PlasmaMutationDetector_1.7.2.zip, r-oldrel: PlasmaMutationDetector_1.7.2.zip
macOS binaries: r-release (arm64): PlasmaMutationDetector_1.7.2.tgz, r-oldrel (arm64): PlasmaMutationDetector_1.7.2.tgz, r-release (x86_64): PlasmaMutationDetector_1.7.2.tgz
Old sources: PlasmaMutationDetector archive

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