Fast Simulation of Bayesian Optimal Interval Designs for Phase I Trials

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Documentation for package ‘simFastBOIN’ version 2.0.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

as.data.frame.boin_boundary	Coerce BOIN Decision Boundaries to a Data Frame
boin_boundary	Integer Decision Boundaries for the BOIN Design
boin_decision_table	Decision Table for the BOIN Design
boin_isotonic	Isotonic Estimates of the DLT Probability
boin_lambda	Escalation and De-escalation Interval Boundaries
boin_p_tox	Toxic Threshold Giving a Required De-escalation Boundary
boin_select_mtd	Select the MTD from Completed Trials
boin_simulate	Simulate BOIN Trials
boin_stopping_table	Safety Stopping Boundary as a Two-Row Table
oc_3p3	Exact Operating Characteristics of the 3+3 Design
plot.boin_decision_table	Plot a BOIN Decision Table
print.boin_boundary	Print BOIN Decision Boundaries
print.boin_decision_table	Print a BOIN Decision Table
print.boin_oc	Print Operating Characteristics of a BOIN Design
print.boin_oc_multi	Print Operating Characteristics Across Scenarios
print.boin_trials	Print Simulated BOIN Trials
print.oc_3p3	Print Operating Characteristics of the 3+3 Design
sim_3p3	Simulate the 3+3 Design
sim_boin	Operating Characteristics of a BOIN Design
sim_boin_multi	Operating Characteristics Across Several Scenarios